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Study on factors affecting TB/HIV co-infection in four counties of China

Shi-Ming CHENG MD, Yu-Ji LAI MS, Er-Yong LIU MS, Lin ZHOU MD, Xue-Jing WANG MS, Qiu-Lan CHEN MS, Dong-Ming LI MS, Ning WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 185-191 doi: 10.1007/s11684-010-0040-7

Abstract: The factors affecting case detection of tuberculosis (TB)/human immunodeficiency virus (HIV) co-infectionHIV test among TB patients and TB examination among people living with HIV/acquired immunodeficiencysyndrome (AIDS) were conducted.Sex, age, ethnic group, occupation, and type of tuberculosis had no significant influence on whetherand extrapulmonary tuberculosis.

Keywords： tuberculosis/acquired immunodeficiency syndrome     dual infection     prevention and control     case detection    

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Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiologyfor tuberculosis control

Chongguang Yang, Qian Gao

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 76-83 doi: 10.1007/s11684-017-0609-5

Abstract:

Tuberculosis (TB) has remained an ongoing concern in China.

Keywords： tuberculosis     recent transmission     molecular epidemiology     China    

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Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 480-489 doi: 10.1007/s11684-017-0594-8

Abstract:

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type

Keywords： human immunodeficiency virus type I     superinfection     incidence     immune response    

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Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 701-713 doi: 10.1007/s11684-022-0951-0

Abstract: A significant clinical challenge in lung cancer treatment is management of the inevitable acquired resistancekey hallmark of cancer and acquisition of apoptosis resistance is accordingly a key mechanism of drug acquiredefficacies and the development of resistance to apoptosis is tightly associated with the emergence of acquiredsensitivity to undergo apoptosis using various means promises an effective strategy for the management of acquired

Keywords： acquired resistance     EGFR inhibitor     apoptosis     lung cancer    

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Co-infection of HIV and parasites in China: Results from an epidemiological survey in rural areas of Fuyang city, Anhui province, China

Li-Guang TIAN MPH, Jia-Xu CHEN PhD, Yu-Chun CAI BM, Jian GUO MPH, Xiao-Mei TONG, Qin LIU DVM, Xiao-Nong ZHOU PhD, Tian-Ping WANG PhD, Xiao-Mei YIN, Wei-Duo WU, Li ZHOU, Feng-Feng WANG, Zhen-Li WANG MSc, Guo-Jin CHENG, Peter STEINMANN PhD, Lan-Hua LI MSc,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 192-198 doi: 10.1007/s11684-010-0039-0

Abstract: The aim of this study was to investigate epidemiological characteristics of co-infection of HIV and intestinal parasites in a HIV/AIDS highly endemic area in China. A cross-sectional survey was carried out in two villages where HIV/AIDS prevalence in residents was over 1%. Stool samples of all residents in the two targeted villages were examined for the presence of intestinal parasites. Blood examination was performed for the HIV infection detection and anemia test. A questionnaire survey was carried out in all residents participating in the study. A total of 769 individuals were enrolled in the investigation, 720 of whom were involved in stool examination of intestinal parasites. The infection rates of parasites in the residents of the targeted villages were as follows: 0.56% for , 4.03% for Hookworm, 0.28% for , 0.42% for , 21.39% for , 3.89% for , 1.67% for spp., 4.44% for spp., and no infection for . The overall infection rate of intestinal worms was 4.72%, intestinal parasite infection rate was 24.31%, the anemia prevalence rate was 34.68%, the co-infection rate of HIV and intestinal helminthes 2.17%, the co-infection rate of HIV and intestinal protozoa 28.26%, of which the co-infection rates of HIV and , and HIV and spp. were 19.57% and 13.04%, respectively. A significant difference of spp. infection rate was found between HIV-positive group (13.04%) and HIV-negative group (4.70%) (<0.05). Higher prevalence of anemia (34.68%) occurred in the study villages, particularly in children (>50%) and women (>39%). It was concluded that the infection rate of intestinal protozoa in the residents was higher than that of intestinal helminthes in the local setting, and a same pattern appeared in the co-infection rate of HIV and parasites. An interesting finding is that the infection rate of spp. among the HIV-positives was significantly higher than that in the HIV-negatives, and children and women had higher anemia prevalence.

Keywords： human immunodeficiency virus (HIV)     acquired immunodeficiency syndrome (AIDS)     co-infection     intestinal    

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Invasive mucinous adenocarcinoma with lepidic-predominant pattern coexisted with tuberculosis: a case

Xinxin Xu, Yinshi Guo, Qiuying Li, Ling Yang, Jianqiang Kang

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 330-333 doi: 10.1007/s11684-017-0545-4

Abstract: invasive mucinous adenocarcinoma (IMA) with a lepidic-predominant pattern accompanied by pulmonary tuberculosisThe patient was treated with several courses of antibiotics and anti-tuberculosis treatments.Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present caseof IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported

Keywords： invasive mucinous adenocarcinoma     lepidic-predominant     tuberculosis    

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lung microbiota and important taxa predicting clinical prognosis in patients with severe community-acquired

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 389-402 doi: 10.1007/s11684-021-0856-3

Abstract: described the key features and prognostic roles of lung microbiota in patients with severe community-acquired

Keywords： severe community-acquired pneumonia     lung microbiota     clinical improvements     7-category ordinal scale    

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bone marrow transplantation in patients with severe aplastic anemia-II that progressed from non-severe acquired

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 718-727 doi: 10.1007/s11684-020-0807-4

Abstract: Severe aplastic anemia II (SAA-II) progresses from non-severe aplastic anemia (NSAA). The unavailability of efficacious treatment has prompted the need for haploidentical bone marrow transplantation (haplo-BMT) in patients lacking a human leukocyte antigen (HLA)-matched donor. This study aimed to investigate the efficacy of haplo-BMT for patients with SAA-II. Twenty-two patients were included and followed up, and FLU/BU/CY/ATG was used as conditioning regimen. Among these patients, 21 were successfully engrafted, 19 of whom survived after haplo-BMT. Four patients experienced grade II–IV aGvHD, including two with grade III–IV aGvHD. Six patients experienced chronic GvHD, among whom four were mild and two were moderate. Twelve patients experienced infections during BMT. One was diagnosed with post-transplant lymphoproliferative disorder and one with probable EBV disease, and both recovered after rituximab infusion. Haplo-BMT achieved 3-year overall survival and disease-free survival rate of 86.4%±0.73% after a median follow-up of 42 months, indicating its effectiveness as a salvage therapy. These promising outcomes may support haplo-BMT as an alternative treatment strategy for patients with SAA-II lacking HLA-matched donors.

Keywords： severe aplastic anemia     non-severe acquired aplastic anemia     haploidentical bone marrow transplantation    

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Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 139-143 doi: 10.1007/s11684-019-0736-2

Abstract: The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults was

Keywords： adult     antibiotic     viral pneumonia    

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Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis

Xiangwei Li, Yu Yang, Jianmin Liu, Feng Zhou, Wei Cui, Ling Guan, Fei Shen, Cong Gao, Mufei Li, Qi Jin, Lei Gao

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 354-366 doi: 10.1007/s11684-013-0257-3

Abstract: directly observed treatment strategy (DOTS), China has made a significant achievement in tackling the tuberculosis

Keywords： tuberculosis     treatment     outcome     China     meta-analysis    

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Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 651-658 doi: 10.1007/s11684-021-0859-0

Abstract: To present the clinical characteristics and the misdiagnosis rate of acute coronary syndrome manifestedcomplaint of throat discomfort, absence of chest pain at onset, and an ultimate diagnosis of acute coronary syndromedyspnea, perspiring, and exertional throat symptoms were significantly associated with acute coronary syndromeThroat discomfort can be the principal manifestation of acute coronary syndrome.throat symptoms, chest tightness, perspiring, and dyspnea were important indicators of acute coronary syndrome

Keywords： acute coronary syndrome (ACS)     throat discomfort (TD)     throat pain     cardiology departments     non-cardiologic    

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Diagnosis and management of acquired thrombotic thrombocytopenic purpura in southeast China: a single

Xinping Zhou,Xingnong Ye,Yanling Ren,Chen Mei,Liya Ma,Jiansong Huang,Weilai Xu,Juying Wei,Li Ye,Wenyuan Mai,Wenbin Qian,Haitao Meng,Jie Jin,Hongyan Tong

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 430-436 doi: 10.1007/s11684-016-0492-5

Abstract:

Acquired thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathyThis study aimed to provide a profile of the diagnosis and management of patients with acquired TTP collectedA total of 60 patients diagnosed with acute acquired TTP from March 2005 to August 2015 were enrolled

Keywords： thrombotic thrombocytopenic purpura     ADAMTS 13     plasma exchange    

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Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 419-426 doi: 10.1007/s11684-014-0383-6

Abstract: of Valsalva has been most extensively documented in the setting of aortopathies, particularly Marfan syndromereview, we carried out a literature search on aneurysmal dilatation of the sinuses of Valsalva in Marfan syndromeIn conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital

Keywords： sinus of Valsalva aneurysms     Marfan syndrome     aortic dissection    

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Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 528-535 doi: 10.1007/s11684-017-0573-0

Abstract:

The prevalence of tuberculosis infection among adolescents born after terminating the Bacillus Calmette

Keywords： tuberculin skin test     interferon-γ release assays     adolescent     agreement    

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Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

Fei Gao, Jingyu Chen, Dong Wei, Bo Wu, Min Zhou

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 224-228 doi: 10.1007/s11684-017-0538-3

Abstract:

Bronchiolitis obliterans syndrome (BOS) after hematopoietic stem cell transplantation (HSCT) is a

Keywords： bronchiolitis obliterans syndrome (BOS)     hematopoietic stem cell transplantation (HSCT)     lung transplantation    

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Title Author Date Type Operation

Study on factors affecting TB/HIV co-infection in four counties of China

Shi-Ming CHENG MD, Yu-Ji LAI MS, Er-Yong LIU MS, Lin ZHOU MD, Xue-Jing WANG MS, Qiu-Lan CHEN MS, Dong-Ming LI MS, Ning WANG MD,

Journal Article

Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiologyfor tuberculosis control

Chongguang Yang, Qian Gao

Journal Article

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Journal Article

Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Journal Article

Co-infection of HIV and parasites in China: Results from an epidemiological survey in rural areas of Fuyang city, Anhui province, China

Li-Guang TIAN MPH, Jia-Xu CHEN PhD, Yu-Chun CAI BM, Jian GUO MPH, Xiao-Mei TONG, Qin LIU DVM, Xiao-Nong ZHOU PhD, Tian-Ping WANG PhD, Xiao-Mei YIN, Wei-Duo WU, Li ZHOU, Feng-Feng WANG, Zhen-Li WANG MSc, Guo-Jin CHENG, Peter STEINMANN PhD, Lan-Hua LI MSc,

Journal Article

Invasive mucinous adenocarcinoma with lepidic-predominant pattern coexisted with tuberculosis: a case

Xinxin Xu, Yinshi Guo, Qiuying Li, Ling Yang, Jianqiang Kang

Journal Article

lung microbiota and important taxa predicting clinical prognosis in patients with severe community-acquired

Journal Article

bone marrow transplantation in patients with severe aplastic anemia-II that progressed from non-severe acquired

Journal Article

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Journal Article

Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis

Xiangwei Li, Yu Yang, Jianmin Liu, Feng Zhou, Wei Cui, Ling Guan, Fei Shen, Cong Gao, Mufei Li, Qi Jin, Lei Gao

Journal Article

Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Journal Article

Diagnosis and management of acquired thrombotic thrombocytopenic purpura in southeast China: a single

Xinping Zhou,Xingnong Ye,Yanling Ren,Chen Mei,Liya Ma,Jiansong Huang,Weilai Xu,Juying Wei,Li Ye,Wenyuan Mai,Wenbin Qian,Haitao Meng,Jie Jin,Hongyan Tong

Journal Article

Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Journal Article

Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Journal Article

Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

Fei Gao, Jingyu Chen, Dong Wei, Bo Wu, Min Zhou

Journal Article